Search details
1.
Ubiquitin ligases: guardians of mammalian development.
Nat Rev Mol Cell Biol
; 23(5): 350-367, 2022 05.
Article
in English
| MEDLINE | ID: mdl-35079164
2.
Author Correction: CIS is a potent checkpoint in NK cell-mediated tumor immunity.
Nat Immunol
; 25(2): 371-372, 2024 Feb.
Article
in English
| MEDLINE | ID: mdl-38087084
3.
CIS is a potent checkpoint in NK cell-mediated tumor immunity.
Nat Immunol
; 17(7): 816-24, 2016 07.
Article
in English
| MEDLINE | ID: mdl-27213690
4.
BTB domain mutations perturbing KCTD15 oligomerisation cause a distinctive frontonasal dysplasia syndrome.
J Med Genet
; 61(5): 490-501, 2024 Apr 19.
Article
in English
| MEDLINE | ID: mdl-38296633
5.
Sequence and structural variations determining the recruitment of WNK kinases to the KLHL3 E3 ligase.
Biochem J
; 479(5): 661-675, 2022 03 18.
Article
in English
| MEDLINE | ID: mdl-35179207
6.
Small molecule inhibitors reveal an indispensable scaffolding role of RIPK2 in NOD2 signaling.
EMBO J
; 37(17)2018 09 03.
Article
in English
| MEDLINE | ID: mdl-30026309
7.
Protocol paper: a multi-center, double-blinded, randomized, 6-month, placebo-controlled study followed by 12-month open label extension to evaluate the safety and efficacy of Saracatinib in Fibrodysplasia Ossificans Progressiva (STOPFOP).
BMC Musculoskelet Disord
; 23(1): 519, 2022 Jun 01.
Article
in English
| MEDLINE | ID: mdl-35650602
8.
Crystal Structure-Guided Design of Bisubstrate Inhibitors and Photoluminescent Probes for Protein Kinases of the PIM Family.
Molecules
; 26(14)2021 Jul 19.
Article
in English
| MEDLINE | ID: mdl-34299628
9.
Lessons from LIMK1 enzymology and their impact on inhibitor design.
Biochem J
; 476(21): 3197-3209, 2019 11 15.
Article
in English
| MEDLINE | ID: mdl-31652302
10.
Target highlights in CASP13: Experimental target structures through the eyes of their authors.
Proteins
; 87(12): 1037-1057, 2019 12.
Article
in English
| MEDLINE | ID: mdl-31442339
11.
Fostering open collaboration in drug development for paediatric brain tumours.
Biochem Soc Trans
; 47(5): 1471-1479, 2019 10 31.
Article
in English
| MEDLINE | ID: mdl-31551357
12.
Covalent targeting of remote cysteine residues to develop CDK12 and CDK13 inhibitors.
Nat Chem Biol
; 12(10): 876-84, 2016 10.
Article
in English
| MEDLINE | ID: mdl-27571479
13.
Activation loop targeting strategy for design of receptor-interacting protein kinase 2 (RIPK2) inhibitors.
Bioorg Med Chem Lett
; 28(4): 577-583, 2018 02 15.
Article
in English
| MEDLINE | ID: mdl-29409752
14.
Structure and inhibitor specificity of the PCTAIRE-family kinase CDK16.
Biochem J
; 474(5): 699-713, 2017 02 20.
Article
in English
| MEDLINE | ID: mdl-28057719
15.
Structural complexity in the KCTD family of Cullin3-dependent E3 ubiquitin ligases.
Biochem J
; 474(22): 3747-3761, 2017 11 01.
Article
in English
| MEDLINE | ID: mdl-28963344
16.
Small molecules dorsomorphin and LDN-193189 inhibit myostatin/GDF8 signaling and promote functional myoblast differentiation.
J Biol Chem
; 290(6): 3390-404, 2015 Feb 06.
Article
in English
| MEDLINE | ID: mdl-25368322
17.
Structures of ABCB10, a human ATP-binding cassette transporter in apo- and nucleotide-bound states.
Proc Natl Acad Sci U S A
; 110(24): 9710-5, 2013 Jun 11.
Article
in English
| MEDLINE | ID: mdl-23716676
18.
Janus kinase inhibition for autoinflammation in patients with DNASE2 deficiency.
J Allergy Clin Immunol
; 145(2): 701-705.e8, 2020 02.
Article
in English
| MEDLINE | ID: mdl-31775019
19.
A small molecule targeting ALK1 prevents Notch cooperativity and inhibits functional angiogenesis.
Angiogenesis
; 18(2): 209-17, 2015 Apr.
Article
in English
| MEDLINE | ID: mdl-25557927
20.
Structural and biochemical characterization of the KLHL3-WNK kinase interaction important in blood pressure regulation.
Biochem J
; 460(2): 237-46, 2014 Jun 01.
Article
in English
| MEDLINE | ID: mdl-24641320